Table 1 Data estimates used for the analysis
From: Optimal management of adults with pharyngitis – a multi-criteria decision analysis
Baseline assumptions | Reference | |
|---|---|---|
Prevalence of Group A Streptococcal infection based on population prevalence of 10% and Centor Score Score = 1 | 3% | 3 |
Score = 2 | 8 % | |
Score = 3 | 19% | |
Score = 4 | 41% | |
Sensitivity of rapid streptococcal antigen test | 84% | 16 |
Specificity of rapid streptococcal antigen test | 93% | 16 |
Sensitivity of throat culture | 78% | 16 |
Specificity of throat culture | 99% | 16 |
Risk of penicillin rash | 2% | 17 |
Risk of anaphylaxis from oral penicillin | 1/10,000 | 17 |
Risk of rheumatic fever if untreated | 5/10,000 | 5, 15 |
Risk of rheumatic fever if treated | 15/100,000 | 5, 15 |
Risk of peri-tonsillar abscess, if untreated | 24/1,000 | 5, 15 |
Risk of peri-tonsillar abscess if treated | 4/1,000 | 5, 15 |