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Table 6 Cohort studies of patients with ARDS published after 1999

From: A Markov computer simulation model of the economics of neuromuscular blockade in patients with acute respiratory distress syndrome

Author Estenssoro46 Luhr47 Davidson48 Arroliga49 Reynolds50 Angus13 Fialkow51
Study type prospective prospective prospective retrospective retrospective prospective retrospective
# of subjects 235 221 127 66 720 200 30
Mean age (yrs) 55 61 39 60   49 51
Severity of illness 21** 19** 73*** 23**   17** 18**
Pa02/FiO2 141 131   111    
ICU days (range)     12   16 (0–93) 21
Ventilator days        
Hospital days (range)    28(1–150)    26 (0–117) 44
3 day mortality 34%       
ICU mortality     47%    47%
In-hospital mortality 58%   43%   36%   
30 day mortality   41%   49%   30.5%  
6 mth mortality       44.3%  
1 yr mortality    47%    44%  
  1. * SAPS; **Apache 2; *** Apache 3