Application of data mining for predicting hemodynamics instability during pheochromocytoma surgery

Table 1 The population characteristics of patients

	Without IHD n = 209 (73.9)	With IHD n = 74 (26.1)	p-value
Demographic characteristics
Mean age (years)	51.9 ± 12.3	54.0 ± 13.8	0.233
Sex (male/female)	110 (52.6) / 99 (47.4)	31 (41.9) / 43 (58.1)	0.112
BMI (kg/m²)	24.1 ± 3.5	21.9 ± 2.7	< 0.001
ASA score 1/2/3	52(24.9)/136(65.1)/21(10.0)	14(18.9)/53(71.6)/7(9.5)	0.548
Comorbidity
Diabetes mellitus	61 (29.2)	23 (31.1)	0.759
Coronary heart disease	66 (31.6)	37 (50.0)	0.005
Hypertension Normal/Intermittent/Continuous	82(39.2)/47(22.5)/80(38.3)	30(40.5)/18(24.3)/26(35.1)	0.883
Arrhythmia	12 (5.7)	4 (5.4)	0.914^b
Preoperative data
Tumor side (left/right)	103 (49.3) / 106 (50.7)	39 (52.7) / 35 (47.3)	0.613
Radiographic tumor size (cm)	5.2 ± 2.5	6.5 ± 3.1	< 0.001
Tumor necrosis	69 (33.0)	33 (44.6)	0.075
Tumor enhanced CT difference (Hu)	43.2 ± 20.6	45.6 ± 20.2	0.435
Use of α adrenoreceptor antagonists	115 (55.0)	42 (56.8)	0.797
Use of crystal/colloid fluid	118 (56.5)	29 (39.2)	0.011
Use of blood transfusion	54 (25.8)	15 (20.3)	0.338
24-h urine metanephrines/ normal upper limit	1.4 (0.9–2.2)	1.47 (0.9–2.7)	0.153^a
Intraoperative data
Laparoscopic vs. Open	109 (52.2) / 100 (47.8)	42 (56.8) / 32 (43.2)	0.495

Continuous variables with normal distribution are reported as the mean ± standard deviation (SD), while non-normal continuous variables as the median (interquartile range) and categorical variables as numbers (percentages). Student’s t-test was used to compare the mean values of two continuous normally distributed variables and the Mann–Whitney U-test was used to determine mean values of two continuous non-normally distributed variables. The chi-squared or Fisher’s exact test was used for categorical variables
^a Mann–Whitney U-test
^b Fisher’s exact test
BMI body mass index; ASA American Society of Anesthesiologists; CT computed tomography; IHD intraoperative hemodynamic instability

ISSN: 1472-6947