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Table 6 Uni- and multi-variable survival analysis for CBMs were performed through KM and Cox proportional hazard model, respectively

From: Leveraging hybrid biomarkers in clinical endpoint prediction

Biomarkers

Univariable

Multivariable

HR

95% CI

HR

95% CI

Demographic factors

Age

  ≤ 70

1

 

1

 

  > 70

2.235

1.097–4.556a

2.257

1.240–4.111

Gender

 Male

1

  

 Female

1.015

0.560–1.837

Weights

  ≤ 150

1

  

  > 150

1.070

0.604–1.897

Smoking Status

 Yes

1

  

 No

1.623

0.872–3.021

Clinical factors

Primary Tumor

  ≤ T2

1

  

  > T2

0.904

0.446–1.830

Lymph Node

 N0

1

 

1

 

  ≥ N1

3.797

1.038–13.887a

4.163

1.858–9.326

Metastasis

 M0

1

  

 M1

4.863

0.238–99.479a

Histology

 Squamous

1

  

 Non-Squamous

1.194

0.582–2.452

Tumor size

 Longest diameter

1.059

1.010–1.110a

 
  1. * representing significant data; HR Hazard ration, CI Confidence interval