Table 12 Comparison of results with other MS studies; ↑ indicates that MS samples have statistically significant increase in predictive metabolic function and ↓ indicates that MS samples have statistically significant decrease in predictive metabolic function; green color indicates agreement of our results and other MS studies; we did not have an MS study to compare with our results in black color
From: Using data science for medical decision making case: role of gut microbiome in multiple sclerosis
Level | Predictive metabolic function | This study | [25] |
|---|---|---|---|
2nd | Signalling molecules and interactions | ↓ |  |
2nd | Energy metabolic functions | ↓ |  |
2nd | Excretory system functions | green↓ | ↓ |
2nd | Signal transduction mechanisms | ↓ |  |
2nd | Replication and repair functions | ↓ |  |
2nd | Amino acid metabolism | green↑ | ↑ |
2nd | lipid metabolism | ↑ |  |
2nd | Inorganic ion transport and metabolism | ↑ |  |
2nd | Unknown functions | ↑ |  |
3rd | Chromosome functions | ↓ |  |
3rd | Peptidases functions | ↓ |  |
3rd | Homologous recombination functions | green↓ | ↓ |
3rd | DNA replication | ↓ |  |
3rd | Peroxisome and cyan amino acid metabolism | ↓ |  |
3rd | Vitamin B6 metabolism | green↓ | ↓ |
3rd | β-alaine metabolism | ↓ |  |
3rd | Inorganic ion transport and metabolism | ↓ |  |
3rd | Mismatch repair functions | ↓ |  |
3rd | Galactose metabolism | ↓ |  |
3rd | Steroid hormone biosynthesis | green↑ | ↑ |
3rd | Tuberculosis functions | ↑ |  |
3rd | Bacterial secretion system | ↑ |  |
3rd | Influenza A | ↑ |  |
3rd | Valine, leucine and isoleucine biosynthesis | ↑ |  |
3rd | Hepatitis C | ↑ |  |
3rd | Cell motility and secretion | ↑ |  |