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Table 4 Regression coefficients of our integrated prognostic model

From: Improving prediction performance of colon cancer prognosis based on the integration of clinical and multi-omics data

Covariate

Coefficient ± SE

HR

95% CI

P

T stage

 T1

 

1

  

 T2

−3.125 ± 1.253

0.0439

0.00377–0.513

0.0127

 T3

−1.186 ± 0.810

0.305

0.0624–1.493

0.143

 T4a

−0.298 ± 1.069

0.742

0.0913–6.033

0.780

 T4b

0.530 ± 1.152

1.699

0.178–16.241

0.646

N stage

 N0

 

1

  

 N1a

0.266 ± 0.504

1.305

0.486–3.506

0.598

 N1b

0.175 ± 0.450

1.191

0.493–2.877

0.697

 N2a

1.355 ± 0.396

3.876

1.785–8.416

0.0006

 N2b

0.985 ± 0.468

2.679

1.071–6.703

0.0352

M stage

 M0

 

1

  

 M1

1.644 ± 0.362

5.178

2.546–10.532

5.64 e-6

Age

 31–58

 

1

  

 59–70

0.654 ± 0.449

1.923

0.798–4.635

0.145

 70–78

1.045 ± 0.411

2.842

1.269–6.363

0.0111

 79–90

1.244 ± 0.382

3.469

1.641–7.333

0.0011

Gene Expression

 Cluster1

 

1

  

 Cluster2

0.970 ± 0.454

2.638

1.083–6.429

0.0328

 Cluster3

2.404 ± 0.551

11.067

3.758–32.591

1.28 e-5

 Cluster4

0.597 ± 1.160

1.817

0.187–17.641

0.606

DNA Methylation

 Cluster1

 

1

  

 Cluster2

−0.138 ± 0.576

0.871

0.281–2.695

0.811

 Cluster3

0.764 ± 0.577

2.146

0.693–6.645

0.185

 Cluster4

0.352 ± 0.465

1.423

0.572–3.539

0.449

 Cluster5

−0.132 ± 0.667

0.876

0.237–3.239

0.843

 Cluster6

−0.895 ± 0.604

0.409

0.125–1.336

0.139

 Cluster7

− 0.397 ± 0.673

0.672

0.180–2.514

0.555

 Cluster8

−1.960 ± 1.128

0.141

0.0155–1.284

0.0822

 Cluster9

−1.848 ± 0.809

0.157

0.0323–0.769

0.0223

 Cluster10

−1.015 ± 0.732

0.362

0.0863–1.521

0.165

miRNA Expression

 Cluster1

 

1

  

 Cluster2

0.527 ± 0.341

1.693

0.867–3.305

0.123

 Cluster3

0.276 ± 0.450

1.318

0.546–3.182

0.539

 Cluster4

−0.669 ± 0.503

0.512

0.191–1.373

0.184

  1. Origin concordance: 0.8345; bias-corrected concordance: 0.7604
  2. SE standard error, HR hazard ratio, CI confidence interval