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Table 5 Difference in discriminative performance between our prognostic model and other models

From: Improving prediction performance of colon cancer prognosis based on the integration of clinical and multi-omics data

Comparison

2-year ∆C ± 95% CI

3-year ∆C ± 95% CI

5-year ∆C ± 95% CI

P value of LRT

CGMm vs CMm

0.0067 ± 0.027

0.0010 ± 0.040

0.0152 ± 0.033

0.00147

CGMm vs CGM

0.0317 ± 0.033

0.0328 ± 0.032

0.0480 ± 0.047

0.000217

CGMm vs CGm

0.0284 ± 0.035

0.0266 ± 0.035

0.0497 ± 0.054

0.000582

CGMm vs CA

0.0349 ± 0.040

0.0497 ± 0.040

0.0694 ± 0.057

0.000312

CGMm vs CG

0.0315 ± 0.037

0.0293 ± 0.031

0.0485 ± 0.049

0.000203

CGMm vs CM

0.0402 ± 0.041

0.0541 ± 0.042

0.0687 ± 0.056

6.919 e-7

CGMm vs Cm

0.0291 ± 0.044

0.0324 ± 0.045

0.0654 ± 0.060

1.528 e-6

CGMm vs C

0.0374 ± 0.040

0.0496 ± 0.042

0.0683 ± 0.054

2.335 e-6

CGMm vs G

0.262 ± 0.12

0.241 ± 0.13

0.268 ± 0.12

2.178 e-12

CGMm vs M

0.143 ± 0.076

0.131 ± 0.079

0.119 ± 0.069

3.426 e-10

CGMm vs m

0.305 ± 0.10

0.259 ± 0.11

0.223 ± 0.15

7.776 e-13

CMm vs CG

0.0247 ± 0.042

0.0284 ± 0.055

0.0333 ± 0.056

0.0118

CMm vs Cm

0.0224 ± 0.035

0.0314 ± 0.040

0.0502 ± 0.054

8.658 e-5

CMm vs C

0.0307 ± 0.040

0.0273 ± 0.052

0.0531 ± 0.061

0.000130

CG vs C

0.00591 ± 0.030

0.0203 ± 0.032

0.0198 ± 0.028

0.000689

Cm vs C

0.00825 ± 0.024

0.0173 ± 0.036

0.00290 ± 0.029

0.270

  1. ∆C difference in C-index, CI confidence interval, LRT likelihood ratio test;
  2. In the Comparisons column, C stands for clinical, G for gene expression, M for DNA methylation and m for miRNA expression. The words on both sides of vs are the covariates in prognostic model