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Table 2 Summary of cross-validated prediction models on trained data (n = 3473)

From: Dementia prediction in the general population using clinically accessible variables: a proof-of-concept study using machine learning. The AGES-Reykjavik study

Model

AUC

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

Model 1

Logistic regression

0.73

[0.71–0.75]

64

[60–68]

70

[68–71]

32

[30–35]

89

[88–91]

Elastic net

0.74

[0.72–0.76]

68

[64–71]

69

[67–71]

33

[31–36]

90

[89–92]

Random forest

0.74

[0.72–0.76]

6

[4–8]

99

[99–99]

60

[47–71]

82

[81–83]

SVM

0.65

[0.62–0.68]

49

[45–53]

73

[71–74]

29

[27–32]

86

[85–88]

Model 2

Logistic regression

0.74

[0.72–0.76]

67

[63–70]

70

[68–72]

34

[31–36]

90

[89–91]

Elastic net

0.74

[0.72–0.76]

67

[63–70]

69

[67–71]

33

[30–36]

90

[89–91]

Random forest

0.74

[0.72–0.76]

47

[43–51]

84

[82–85]

40

[36–44]

88

[86–89]

SVM

0.73

[0.71–0.75]

72

[69–76]

63

[61–65]

31

[28–33]

91

[89–92]

Model 3

Logistic regression

0.71

[0.68–0.74]

64

[60–68]

68

[66–70]

31

[29–34]

89

[88–91]

Elastic net

0.71

[0.68–0.74]

64

[60–67]

67

[65–69]

31

[28–33]

89

[88–90]

Random forest

0.71

[0.68–0.74]

55

[51–59]

75

[73–77]

34

[31–37]

88

[87–89]

SVM

0.70

[0.67–0.73]

69

[65–73]

61

[59–63]

29

[27–31]

90

[88–91]

  1. AUC = area under the ROC curve. SVM = support vector machine