Table 1 Prevalence of cardio-renal-metabolic conditions overall and by socio-demographic in the CPRD Aurum database, 2020
All | Aortic aneurysm | Atrial fibrillation (AF) | (CKD) (clinical codes) | CKD (latest eGFR < 60) | Diabetes (Type 1) | Diabetes (all) | Heart failure | Heart valve disorders | Hypertension (clinical codes) | Hypertension (BP > 140/ 90) * | Ischaemic heart disease (IHD) | Peripheral vascular disease (PVD) | Stroke | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Number (%) | 12,361,554 | 33,292 (0.27) | 260,966 (2.11) | 431,791 (3.49) | 505,860 (4.09) | 60,342 (0.49) | 721,301 (5.84) | 166,273 (1.35) | 169,116 (1.37) | 1,885,400 (15.25) | 4,003,524 (32.39) | 481,846 (3.90) | 82,890 (0.67) | 207,911 (1.68) |
Age (median, IQR) | 39.5 (22.5–58.5) | 76.5 (69.5–83.5) | 77.5 (69.5–84.5) | 78.5 (70.5–85.5) | 79.5 (71.5–85.5) | 49.5 (34.5–62.5) | 66.5 (55.5–75.5) | 76.5 (66.5–84.5) | 74.5 (60.5–82.5) | 69.5 (58.5–77.5) | 59.5 (46.5–71.5) | 73.5 (63.5–81.5) | 74.5 (66.5–81.5) | 72.5 (60.5–81.5) |
Age Categories (years) | ||||||||||||||
0–16 | 2,215,109 (17.9) | 48 (< 0.01) | 24 (< 0.01) | 233 (0.01) | 88 (< 0.01) | 4,026 (0.18) | 4,118 (0.19) | 726 (0.03) | 6,455 (0.29) | 2,383 (0.11) | 14,987 (0.68) | 2,215,109 (0.01) | 94 (< 0.01) | 1,135 (0.05) |
17–30 | 2,157,953 (17.5) | 103 (< 0.01) | 578 (0.03) | 833 (0.04) | 842 (0.04) | 10,276 (0.48) | 13,394 (0.62) | 1,542 (0.07) | 7,693 (0.36) | 18,104 (0.84) | 276,207 (12.80) | 2,157,953 (0.15) | 220 (0.01) | 3,093 (0.14) |
31–40 | 1,808,259 (14.6) | 178 (0.01) | 2,018 (0.11) | 2,649 (0.15) | 2,390 (0.13) | 8,774 (0.49) | 26,084 (1.44) | 2,311 (0.13) | 6,993 (0.39) | 45,803 (2.53) | 374,226 (20.70) | 1,808,259 (0.31) | 490 (0.03) | 5,744 (0.32) |
41–50 | 1,676,254 (13.6) | 377 (0.02) | 5,607 (0.33) | 8,149 (0.49) | 7,082 (0.42) | 9,426 (0.56) | 67,810 (4.05) | 5,266 (0.31) | 9,142 (0.55) | 137,914 (8.23) | 574,506 (34.27) | 1,676,254 (1.03) | 1,784 (0.11) | 12,141 (0.72) |
51–60 | 1,704,779 (13.8) | 1,128 (0.07) | 18,211 (1.07) | 27,555 (1.62) | 25,646 (1.50) | 11,039 (0.65) | 142,704 (8.37) | 15,240 (0.89) | 16,311 (0.96) | 336,486 (19.74) | 842,262 (49.41) | 1,704,779 (3.45) | 8,173 (0.48) | 27,771 (1.63) |
61–70 | 1,254,678 (10.2) | 7,234 (0.58) | 40,984 (3.27) | 62,122 (4.95) | 66,026 (5.26) | 8,157 (0.65) | 175,564 (13.99) | 27,881 (2.22) | 24,365 (1.94) | 447,809 (35.69) | 768,883 (61.28) | 1,254,678 (8.43) | 18,915 (1.51) | 40,294 (3.21) |
70+ | 1,544,522 (12.5) | 24,224 (1.57) | 193,544 (12.53) | 330,250 (21.38) | 403,786 (26.14) | 8,644 (0.56) | 291,627 (18.88) | 113,307 (7.34) | 98,157 (6.36) | 896,901 (58.07) | 1,152,453 (74.62) | 1,544,522 (18.84) | 53,214 (3.45) | 117,733 (7.62) |
Sex | ||||||||||||||
Male | 6,224,433 (50.4) | 27,081 (0.4) | 150,874 (2.4) | 180,645 (2.9) | 222,605 (3.6) | 34,163 (0.5) | 401,806 (6.5) | 94,485 (1.5) | 81,494 (1.3) | 931,858 (15.0) | 1,922,607 (30.9) | 298,464 (4.8) | 52,627 (0.8) | 108,374 (1.7) |
Female | 6,137,121 (49.6) | 6,211 (0.1) | 110,092 (1.8) | 251,146 (4.0) | 283,255 (4.6) | 26,179 (0.4) | 319,495 (5.1) | 71,788 (1.2) | 87,622 (1.4) | 953,542 (15.3) | 2,080,917 (33.4) | 183,382 (2.9) | 30,263 (0.5) | 99,537 (1.6) |
Ethnicity | ||||||||||||||
White | 7,919,608 (64.1) | 27,395 (0.4) | 213,108 (2.7) | 337,649 (4.3) | 398,122 (5.0) | 45,195 (0.6) | 493,914 (6.2) | 129,746 (1.6) | 130,422 (1.6) | 1,417,789 (17.9) | 2,942,191 (37.2) | 375,726 (4.7) | 67,323 (0.9) | 159,183 (2.0) |
Asian | 1,024,958 (8.3) | 658 (0.1) | 5,149 (0.5) | 18,971 (1.9) | 22,271 (2.2) | 3,226 (0.3) | 96,601 (9.4) | 8,210 (0.8) | 7,310 (0.7) | 119,782 (11.7) | 267,799 (26.1) | 32,367 (3.2) | 2,507 (0.2) | 9,435 (0.9) |
Black | 508,581 (4.1) | 385 (0.1) | 2,945 (0.6) | 14,181 (2.8) | 11,096 (2.2) | 2,373 (0.5) | 43,021 (8.5) | 4,882 (1.0) | 3,982 (0.8) | 87,138 (17.1) | 158,031 (31.1) | 9,068 (1.8) | 1,612 (0.3) | 6,396 (1.3) |
Mixed ethnicity | 207,281 (1.7) | 114 (0.1) | 860 (0.4) | 2,709 (1.3) | 3,597 (1.7) | 707 (0.3) | 8,524 (4.1) | 981 (0.5) | 1,139 (0.5) | 16,856 (8.1) | 41,572 (20.1) | 2,738 (1.3) | 375 (0.2) | 1,430 (0.7) |
Other ethnicity | 171,985 (1.4) | 112 (0.1) | 838 (0.5) | 1,488 (0.9) | 1,879 (1.1) | 447 (0.3) | 6,853 (4.0) | 747 (0.4) | 1,046 (0.6) | 12,037 (7.0) | 34,684 (20.2) | 2,856 (1.7) | 294 (0.2) | 1,046 (0.6) |
Missing | 2,529,141 (20.5) | 4,628 (0.2) | 38,066 (1.5) | 56,793 (2.2) | 68,895 (2.7) | 8,394 (0.3) | 72,388 (2.9) | 21,707 (0.9) | 25,217 (1.0) | 231,798 (9.2) | 559,247 (22.1) | 59,091 (2.3) | 10,779 (0.4) | 30,421 (1.2) |
Deprivation quintile | ||||||||||||||
1 least deprived | 2,438,403 (19.7) | 7,237 (0.3) | 63,537 (2.6) | 92,147 (3.8) | 109,168 (4.5) | 11,610 (0.5) | 116,807 (4.8) | 31,930 (1.3) | 39,387 (1.6) | 386,861 (15.9) | 816,779 (33.5) | 97,006 (4.0) | 13,619 (0.6) | 39,700 (1.6) |
2 | 2,405,342 (19.5) | 7,183 (0.3) | 59,183 (2.5) | 91,519 (3.8) | 108,591 (4.5) | 11,727 (0.5) | 129,822 (5.4) | 33,172 (1.4) | 36,872 (1.5) | 386,346 (16.1) | 812,461 (33.8) | 97,405 (4.0) | 15,069 (0.6) | 40,319 (1.7) |
3 | 2,330,927 (18.9) | 6,440 (0.3) | 50,315 (2.2) | 82,878 (3.6) | 98,441 (4.2) | 11,330 (0.5) | 135,457 (5.8) | 31,067 (1.3) | 31,679 (1.4) | 358,810 (15.4) | 759,158 (32.6) | 91,305 (3.9) | 15,270 (0.7) | 39,128 (1.7) |
4 | 2,512,131 (20.3) | 6,069 (0.2) | 43,970 (1.8) | 80,012 (3.2) | 94,289 (3.8) | 11,982 (0.5) | 157,097 (6.3) | 32,438 (1.3) | 29,912 (1.2) | 365,489 (14.5) | 778,630 (31.0) | 90,960 (3.6) | 17,081 (0.7) | 42,975 (1.7) |
5 most deprived | 2,368,487 (19.2) | 5,524 (0.2) | 38,018 (1.6) | 75,068 (3.2) | 83,881 (3.5) | 11,895 (0.5) | 163,902 (6.9) | 33,808 (1.4) | 27,041 (1.1) | 340,040 (14.4) | 728,575 (30.8) | 92,713 (3.9) | 20,027 (0.8) | 40,884 (1.7) |
Missing deprivation | 300,458 (2.5) | 839 (0.3) | 5,943 (1.9) | 10,167 (3.3) | 11,490 (3.8) | 1,798 (0.6) | 18,216 (6.0) | 3,858 (1.3) | 4,225 (1.4) | 47,854 (15.6) | 107,921 (35.2) | 12,457 (4.1) | 1,824 (0.6) | 4,905 (1.6) |