Table 5 Characterisation of the four resulting clusters obtained from HF dataset. Continuous variables are described as median (inter-quartile range) and categorical variables as %. p-values for the comparison of the characteristics across clusters

Number of Patients

789

866

1231

859

3745

-

Female, %

37.39

63.51

40.54

73.92

52.84

< 0.01

Male, %

62.61

36.49

59.46

26.08

47.16

< 0.01

Age, years

85.0(78.0-89.0)

81.0(73.0-87.0)

83.0(76.0-89.0)

76.0(59.5-85.0)

82.0(73.0-88.0)

< 0.01

BMI, kg/m²

24.69(23.31-29.0)

26.14(24.16-31.09)

24.27(23.21-25.7)

24.83(23.44-27.06)

24.8(23.44-27.78)

< 0.01

Ischemic Cardiomyopathy, %

49.43

25.87

17.3

8.73

24.09

< 0.01

Cardiomyopathy, %

7.73

9.93

1.79

4.31

5.5

< 0.01

Hypertension, %

70.22

84.53

52.07

22.35

56.58

< 0.01

Diabetes, %

30.42

16.17

6.17

1.16

12.44

< 0.01

Atrial fibrillation, %

55.64

45.5

22.5

18.04

33.78

< 0.01

Transient Ischemic Attack, %

26.62

17.55

5.85

2.44

12.15

< 0.01

Valvular Disease, %

29.91

24.6

12.19

4.77

17.09

< 0.01

Chronic Kidney Disease, %

74.52

21.48

12.75

0.35

24.94

< 0.01

Anaemia, %

88.47

10.62

99.35

0.0

53.75

< 0.01

COPD, %

24.59

12.47

6.66

2.56

10.84

< 0.01

Obesity, %

25.86

33.95

6.99

11.64

18.26

< 0.01

Number of ICD-9 Codes

14.0(8.0-23.0)

10.0(6.0-16.0)

5.0(2.0-9.0)

4.0(2.0-7.0)

7.0(3.0-13.0)

< 0.01

Number of Chronic Diseases

8.0(6.0-10.0)

6.0(5.0-8.0)

4.0(2.0-5.0)

3.0(2.0-4.0)

5.0(3.0-7.0)

< 0.01

Sodium, mEq/L

140.0(137.0-143.0)

140.0(138.0-142.0)

139.56(137.0-142.0)

139.51(139.0-141.0)

139.57(138.0-142.0)

< 0.01

Urea, mg/dL

81.0(53.0-120.0)

51.0(39.0-68.0)

56.64(43.0-78.0)

44.94(35.78-55.67)

54.0(40.0-79.0)

< 0.01

Creatinin, mg/dL

1.68(1.22-2.36)

1.1(0.89-1.34)

1.23(0.98-1.52)

1.01(0.83-1.16)

1.17(0.93-1.56)

< 0.01

Hemoglobin, g/dL

10.7(9.3-11.9)

13.3(12.1-14.4)

11.0(9.8-12.3)

13.4(12.47-14.2)

12.19(10.6-13.4)

< 0.01

Red Cell Distribution Width, %

15.7(14.4-17.3)

14.39(13.4-15.3)

14.89(14.3-16.3)

14.3(13.4-14.75)

14.69(13.8-15.9)

< 0.01

Platelet count, x10³/L

209.0(152.0-264.0)

214.0(172.0-253.81)

225.0(182.0-276.0)

238.0(193.5-264.0)

223.0(176.0-263.08)

< 0.01

NT-proBNP, pg/ml

4873.0(1648.0-13342.0)

1440.5(402.5-4083.19)

3817.0(1455.0-6973.7)

2173.0(531.5-4275.74)

2800.1(942.0-6255.0)

< 0.01

Number of Consultations/year

4.5(1.0-12.5)

3.5(1.0-8.5)

01.0(0.0-3.5)

1.0(0.0-3.5)

2.0(0.5-6.0)

< 0.01